TMP/SMX works well for UTI treatment in general. Together, the powerful combination blocks two important steps required for certain bacteria to make the proteins they need to survive. How it Works: Trimethoprim/sulfamethoxazole (generic Bactrim) is a combination drug containing two antibiotics: trimethoprim and sulfamethoxazole. Trimethoprim/sulfamethoxazole (Bactrim, Septra) Here are a few important facts about those three. Trimethoprim/sulfamethoxazole, nitrofurantoin, and fosfomycin are the most preferred antibiotics for treating a UTI. Not all antibiotics work for treating UTIs, but several do. If you have a fungal or viral UTI, antibiotics won’t help. It’s worth noting that antibiotics only treat UTIs and other infections caused by bacteria. They either stop those bacteria from growing or directly kill the bacteria altogether.
If you have a bacterial UTI, the only way to treat it is by getting rid of the bacteria that’s causing it. UTIs can be caused by many different types of germs including bacteria or fungi - and in rare cases, even viruses.
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